Cancer Doubling Concept

  • Most solid tumors tend to double in volume at approximately the same rate throughout the majority of their life spans, with possible slow-down very early and/or at the end.
  • There is a small body of literature published in the 1960s-80s in which the growth of these tumors was measured over time; means and ranges were calculated for the more common tumor types.These curves tend to follow a bell-shaped curve, adding to the likelihood of their reliability.
  • Generally, the more rapid the doubling time, the more aggressive the tumor. The average breast cancer doubles about every 125 days, for example, but very aggressive tumors have been described as doubling as rapidly as every 2-3 days; less aggressive at every 300 days or more.

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